Our lab is interested in the role of sleep and circadian regulation in metabolic homeostasis. Specifically, we study how sleep and circadian disruption impair metabolic tissues and whether improving the timing of behaviors such as sleep, exercise and eating can improve metabolic health.
Broussard JL, Perreault L, Macias E. Newsom SA, Harrison K, Bui HH, Milligan P, Roth KD, Nemkov T, D’Alessandro A, Brozinick JT, Bergman BC. Sex differences in insulin sensitivity are related to muscle tissue acylcarnitine but not subcellular lipid distribution. Obesity. 2021. In press.
Thomas EA, Zaman A, Cornier M, Catenacci VA, Tussey EJ, Grau L, Arbet J, Broussard JL, Rynders CA. Later Meal and Sleep Timing Predicts Higher Percent Body Fat. Nutrients, 13(1), 73. 2021.
Rynders CA, Morton SJ, Bessesen DH, Wright KP Jr., Broussard JL. Circadian rhythm of substrate oxidation and hormonal regulators of energy balance. Obesity. 22 May 2020. doi:10.1002/oby.22816.
Brouwer A, Bediako IA, Paszkiewicz RL, Kolka CM, Bergman RN, Broussard JL. Impact of sleep deprivation and high-fat feeding on insulin sensitivity and beta cell function in dogs. Diabetologia, 63(4), 875-884. DOI 10.1007/s00125-019-05084-5. View in: PubMed
Broussard JL, Reynolds AC, Depner CM, Ferguson SA, Dawson D, Wright KP. Jr. Circadian Rhythms versus Daily Patterns in Human Physiology and Behavior; pp 279-295. In V. Kumar Ed. Biological Timekeeping: Clocks, Rhythms and Behaviour. 2017.
Broussard JL, Van Cauter E. Disturbances of sleep and circadian rhythms: novel risk factors for obesity. Curr Opin Endocrinol Diabetes Obes. 2016 Oct; 23(5):353-9. View in: PubMed
Broussard JL, Devkota S. The changing microbial landscape of Western society: Diet, dwellings and discordance. Mol Metab. 2016 Sep; 5(9):737-42. View in: PubMed
Broussard JL, Kilkus JM, Delebecque F, Abraham V, Day A, Whitmore H, Tasali E. Elevated ghrelin predicts food intake during experimental sleep restriction. Obesity. 2016; 24(1):132-8.
Broussard JL, Kolka C, Castro AVB, Asare IB, Paszkiewicz RL, Szczepaniak EW, Szczepaniak LS, Knutson KL, Kim SP, Bergman RN. Elevated nocturnal NEFA are an early signal for hyperinsulinemic compensation during diet-induced insulin resistance. Diabetologia. 2015; 58(11):2663-70.
Broussard JL, Chapotot F, Abraham V, Day A, Delebecque F, Whitmore H, Tasali E. Sleep restriction increases free fatty acids in healthy men. Diabetologia. 2015; 58(4):791-798.
Broussard JL, Ehrmann D, Van Cauter E, Tasali E, Brady M. Experimental Reduction of Sleep Duration Is Associated with Impaired Insulin Signaling in the Adipocyte. Ann Intern Med. 2012 Oct 16;157(8):549-57.
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