The SAM Lab is interested in the role of sleep and circadian regulation in metabolic and cardiovascular homeostasis. Specifically, we study how sleep and circadian disruption impair whole body and tissue-specific function, and whether improving the timing of behaviors such as sleep, exercise and eating can improve health and reduce disease risk.
CURRENT RESEARCH PROJECTS
Incubating
(Coming soon!)
Proliferating
(Coming soon!)
Differentiating
(Coming soon!)
SELECT RECENT PUBLICATIONS
(TRAINEES IN BLUE)
For a comprehensive publication list, please click here.
Aggarwal B, Gao Y, Alfini A, Azarbarzin A, Anafi RC, Baron KG, Bautch VL, Bowles N, Broussard JL, Brown M, Cheng P, Cook SH, Cortese R, Fernandez F-X, Galis Z, Johnson DA, Jelic S, Lipton JO, Lutsey PL, Miao Q, Ordovas JM, Prather AA, Swirski FK, Tasali E, Vargas I, Grandner MA, Lloyd-Jones D. Sleep and circadian rhythms in cardiovascular resilience: mechanisms, implications, and a Roadmap for research and interventions. Nat Rev Cardiol (2025). https://doi.org/10.1038/s41569-025-01188-1.
Simé Mora, G., Lowry, C. G., Lyon, E. J., Biela, L. M., Thompson, D. P., Hickey, M. S., Rynders, C. A., Broussard, J. L. Through-the-Wall Blood Sampling Method to Minimize Sleep Disruption in Clinical Settings. J. Vis. Exp. (220), e67530, doi:10.3791/67530 (2025).
Hanlon EV, Tasali E, Broussard JL. 2025. Principles and Practice of Sleep Medicine. 8th edition. Chapter 27: Endocrine Physiology in Relation to Sleep and Sleep Disturbances.
Trikha, S.R.J., Raab, R., DeZeeuw, T, Moore, S., Neagle, M., Petrun, M., Broussard JL. Prevalence and predictors of obstructive sleep apnea in collegiate football players. J Clin Sleep Med 2025. https://doi.org/10.5664/jcsm.11646.
Dashti HS, Jansen EC, Zuraikat FM, Dixit S, Brown M, Laposky A, Broussard JL, Butler M, Creasy SA, Crispim CA, Depner CM, Esser K, Garaulet M, Hanlon EC, Makarem N, Manoogian ENC, Peterson CM, Scheer FAJL, Wright KP Jr, Goff DC Jr, Pratt CA, Gamble KL, St-Onge MP. Advancing Chrononutrition for Cardiometabolic Health: A 2023 National Heart, Lung, and Blood Institute Workshop Report. Journal of the American Heart Association 2025, e039373 https://doi.org:doi:10.1161/JAHA.124.039373.
Seward SL, Kishman EE, Rynders, CA, Broussard JL. Acute night shift work is associated with increased blood pressure and reduced sleep duration in healthy adults. Physiol Rep 13, e70231 (2025). https://doi.org:10.14814/phy2.70231.
Rynders CA and Broussard JL. Running the Clock: New Insights into Exercise and Circadian Rhythms for Optimal Metabolic Health (Editorial). Journal of Physiology, 2024 Dec;602(23):6367-6371. doi: 10.1113/JP287024.
Kishman EE, Sirimon R, Broussard JL. Metabolic consequences of sleep and circadian disruption during pregnancy and postpartum. Trends in Endocrinology and & Metabolism. 2024 Sep 18:S1043-2760(24)00243-1.
Broussard JL, Garfield A, Zarini S, Brozinick JT, Perreault L, Newsom SA, Kahn D, Kerege A, Zemski Berry K, Bui HH, Bergman BC. Combined diet and exercise training decreases serum lipids associated with insulin resistance. Obesity, 2024 Dec;32(12):2334-2344.
Singh P, Beyl RA, Stephens JM, Richard AJ, Boudreau A, Hebert RC, Noland RC, Burk DH, Ghosh S, Staszkiewicz J, Salbaum JM, Broussard JL, St-Onge MP, Ravussin E, Marlatt KL. Shortened sleep duration impairs adipose tissue adrenergic stimulation of lipolysis in postmenopausal women. Obesity, 2024 Dec;32(12):2264-2274. doi: 10.1002/oby.24162.
Singh P, Beyl RA, Stephens JM, Noland RC, Richard AJ, Boudreau A, Hebert RC, Ravussin E, Broussard JL, St-Onge M-P, Marlatt KL. Effect of sleep restriction on insulin sensitivity and energy metabolism in postmenopausal women: A randomized, crossover trial. Obesity. 2023. Mar 30. doi: 10.1002/oby.23739.
Broussard JL, Knud-Hansen BC, Grady S, Knauer OA, Ronda JM, Aeschbach D, Czeisler CA, Wright KP, Jr. Influence of circadian phase and extended wakefulness on glucose levels during forced desynchrony. Sleep Health. 2023 Nov 22:S2352-7218(23)00247-4.
Erickson ML, Dobias D, Keleher MR, Dabelea D, Bergman BC, Broussard JL, Boyle KE. In Vitro Circadian Clock Gene Expression Assessments in Mesenchymal Stem Cells from Human Infants: A Pilot Study. Nutrients. 2023 Dec 23;16(1):52. doi: 10.3390/nu16010052. PMID: 38201882.
Chaput JP, McHill AW, Cox RC, Broussard JL, Dutil C, da Costa BGG, Sampasa-Kanyinga H, Wright KP Jr. The role of insufficient sleep and circadian misalignment in obesity. Nat Rev Endocrinol. 2023 Feb;19(2):82-97. doi: 10.1038/s41574-022-00747-7. PMID: 36280789.
2025
2024 - 2023